Malaria Parasites: Comparative Genomics, Evolution and Molecular Biology
Publisher: Caister Academic Press
Editor: Jane M. Carlton, Susan L. Perkins and Kirk W. Deitsch Center for Genomics and Systems Biology, Department of Biology, New York University, USA; Sackler Institute for Comparative Genomics, New York, USA; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, USA (respectively)
Publication date: February 2013
ISBN: 978-1-908230-07-2
Price: GB £159  (hardback)
Pages: c. 280

This wealth of genome sequence data has provided researchers with a powerful new tool, comparative genomics, which has revolutionised research in this area. In this book, expert authors from around the world comprehensively review the current advances in Plasmodium comparative genomics, highlighting the fascinating new insights into parasite evolution and molecular biology that have ensued. Topics include: Plasmodium taxonomy and phylogeny; the apicomplexan genomic landscape; the "art" of sequencingPlasmodium genomes; diversity of Plasmodium falciparum and Plasmodium vivax genomes; Plasmodium functional genomics; Plasmodium experimental genetic crosses; P. falciparum epigenetic modification and transcriptional regulation; Plasmodium invasion of host red blood cells; protein export and trafficking by malaria parasites; Plasmodium-mosquito vector interactions; and a practical guide to many of the revolutionary new techniques and molecular tools for Plasmodium research. The book is essential reading for every researcher working with malaria parasites and related organisms, from the PhD student to the experienced scientist, and is a recommended text for all parasitologists.